JASSA v4
Joined Advanced Sumoylation Site and Sim Analyser
by BEAUCLAIR Guillaume
1: Input parameters
Type or paste your sequence (protein or cDNA or mRNA)...
Or UniProt Entry Protein ID...
Or upload FASTA file (.fasta/fas/fa/... or .txt)
(ex P12345)
Sequence name (Optional)
PDB id (Optional)
2: Output parameters
Analyse with: (Informations) Results SUMO (Informations)
Motifs: (Informations) Results SIM (Informations)
Special environment (Informations) Output setting (Informations)
3: Start analyse
[-] Patterns list
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s		 Consensus direct Stong consensus direct [Ψ]-[K]-[x]-[α] Ψ = I,L, or V; α = D or E Melchior, 2000
Rodriguez, 2001
Consensus direct Ψ = A,F,I,L,M,P,V or W; α = D or E
Weak consensus direct Ψ = A,F,G,I,L,M,P,V,W or Y; α = D or E
PDSM [Ψ]-[K]-[x]-[α]-[x]2-[S]-[P] Ψ = A,F,I,L,M,P,V or W; α = D or E Hietakangas, 2006
Extended PDSM [Ψ]-[K]-[x]-[α]-[x]2-[S/T]-[P](0-1) Ψ = A,F,I,L,M,P,V or W; α = D or E
NDSM [Ψ]-[K]-[x]-[α]-[x]-[α]6 Ψ = A,F,I,L,M,P,V or W; 2 out of 6 α must be D or E Yang, 2006
HCSM [Ψ]3-[K]-[x]-[E] Ψ = A,F,G,I,L,P or V Matic, 2010
SC-SUMO [P/G]-[x](0-3)-[I/V]-[K]-[x]-[E]-[x](0-3)-[P/G]   Benson, 2007
Minimal SC-SUMO [I/V]-[K]-[x]-[E]-[x](0-3)-[P] Subramanian, 2003
SUMO-Acetyl switch [Ψ]-[K]-[x]-[α]-[P] Ψ = A,F,I,L,M,P,V or W; α = D or E Stankovic-Valentin, 2007
pSuM [Ψ]-[K]-[x]-[pS]-[P] Ψ = A,F,I,L,M,P,V or W
pS/T = phosphorylated serine/threonine		 Picard, 2012
Extended pSuM [Ψ]-[K]-[x]-[pS]-[P]-[pS/T](0-1)-[x]3-[pS/T](0-1)-[P]
Consensus Inverted Strong consensus inverted [α]-[x]-[K]-[Ψ] Ψ = I,L or V; α = D or E Ivanov, 2007
Matic, 2010
Consensus inverted Ψ = A,F,I,L,M,P,V or W; α = D or E
Weak consensus inverted Ψ = A,F,G,I,L,M,P,V,W or Y; α = D or E
Putative SIM sites SIM Type 1 [Ψ]-[Ψ]-[x]-[Ψ] Ψ = I, L, V; α = D or E Beauclair, Submitted
SIM Type 2 [Ψ]-[x]-[Ψ]-[Ψ]
SIM Type 3 [Ψ]-[Ψ]-[Ψ]-[Ψ]
SIM Type 4 [x]-[Ψ]-[Ψ]-[Ψ]
SIM Type 5 [Ψ]-[α]-[Ψ]-[α]-[Ψ]
SIM Type α [V/I]-[x]-[V/I]-[V/I]   Song, 2004
SIM Type β [V/I]-[V/I]-[x]-[V/I/L]
SIM Type a [P/I/L/V/M]-[I/L/V/M]-[x]-[I/L/V/M]-[α/S]3 α = D or E Miteva, 2010
Sun, 2012
SIM Type b [P/I/L/V/M/F/Y]-[I/L/V/M]-[D]-[L]-[T]
SIM Type r [α/S]3-[I/L/V/M]-[x]-[I/L/V/M/F]2
SIM Type H [K]-[x]3-5-[I/V]-[I/L]-[I/L]-[x]3-[D/E/Q/N]-[α]2 α = D or E Hannich, 2005
SIM Type M [Ψ]2-[x]-[S]-[x]-[S/T]-[α]3 Ψ = hydrobobic amino acid; α = acidic amino acid Minty, 2000
Special environment Serine or Acid amino acid (For SIM) [S/D/E]   Hecker, 2006
Potentially phosphorylated amino acid [S/T/Y]    
Acid amino acid [D/E]    
Hydrophobic and/or nonpolar amino acid [A/F/I/L/M/P/V/W]    
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